The authors reviewed 359 cases which had fine needle aspiraton cytology(FNAC) of breast mass from Jan. 1991 at Departmnet of Surgery, Korea Cancer Center Hospital.
The diagnostic accuracy of clinical examination, mammography, and FANC was compared with definitive histological findings in 118 cases among the 359 cases.
@ES The results from three diagnostic methods were as follows:
@EN 1) Clinical diagnosis based on history and physical examination had 92.6% of sensitivity, 68% of specificity, and 82% of diagnostic accuracy.
2) Mammography had 70.6% of sensitivity, 82% of specificity, and 75.4% of diagnostic accuracy.
3) Based on histopathologic diagnosis, FNAC had 94% of sensitivity, 5.9% of false negative, 94.4% of specificity. 5.5% of false positive, 89.5% of negative predictive value, 96.9% of positive predictive value, and 94.2% of diagnostic accuracy.
No
patient with malignant cytology was subsequently shown to have benign disease.
FNAC is a less invasive procedure that appears to be superior to physical examination and mammography in establishing the diagnosis of clinically suspicious breast masses. However, clinical examination and mammography remain important procedures
because
they can identify malignant lesions which cytology fails to do and also because some carcinomas can only be detected mammographically.
We concluded that a combination of clinical examiniation and mammography, with fine needle aspiration cytology performed by experienced surgeons with a good technique and interpreted by experienced pathologists, can identify all patients with
breast
cancer before surgery.
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